BIOHEART, INC.

Welcome to Bioheart MicroImplants

The Main Focus of Bioheart MicroImplants is Myocardial Tissue Engineering. Explore this section of the site for the latest Bioheart Products and Services related to this exciting field.

Be sure to visit our Online Interactive Resources page for the latest news and information in this exciting field of research.

Bibliography of Papers from Bioheart Research Team Members: Research on Myoblast and Stem Cell Injections into Myocardium for Heart Muscle Regeneration (MYOGENESIS) Click Here.

View Our Interactive Resources!

Importance of Nitric Oxide Synthase Slideshow

Summary: Animal and
In Vitro Test Sites

New Flow Chart...Click Here!

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Myocardial Tissue Engineering BIOHEART MicroImplants

First Product (under development)

Heart Muscle Regeneration (MYOGENESIS) System (under development) - Autologous immature myoblasts (cultured and processed in Bioheart controlled labs with 17 step proprietary method) injected into damaged myocardium to ATTEMPT TO repopulate, re-vascularize (arteriogenesis), regenerate and improve diastolic and systolic function of treated region. CAUTION: This attempted improvement is yet to be proven in statistically appropriate controlled clinical trials. Cells are injected with 25g bent needle, thorocoscopic needle probe or endovascular needle catheter (7FR) with deflecting tip and dial in needle depth control.

Future Products

Heart Muscle Regeneration (MYOGENESIS) System (under development) - Immature myoblasts transvected with eNOS mixed with bone marrow, stromal cells, Angiopoiten 1 Tie Receptors, L-Arginine, Pyruvate, VEGF/FGF, Fibrinogen Matrix, Endothelial Cells & Fibrin Glue.


These are illustrations of the proposed method of heart muscle regeneration under development deflecting guide catheter with slidable inner needle assembly for delivery of cellular implants into myocardium wall.

Related Information
Implant Delivery
Device Components
Brief Summary of
Pre-Clinical Animal Studies

Feel free to click on the images to take a better look at the finer details of these interesting illustrations!

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(file sizes approximately 281k)

Illustration of Method Photo 1... Illustration of Method Photo 2...



FIU

FIU-CVEC Image


We are now occupying space at the Cardiovascular Engineering Center (CVEC) of Florida International University. CVEC faculty and staff are now collaborating with us in a research project. Go There!
Cambridge, Massachusetts
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MSNBC Video on Angiogenesis

(Requires Windows Media Player)
The American Heart Association reports only 2,300 of the 40,000 Americans who needed a new heart in 1997 got one.
 

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Interactive Resources

 

Bioheart Bioblasts
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